Table 1.
Structural characteristics of gangliosides and related compounds utilized in this study
| Moleculea | Schematic structure |
|---|---|
| N-Acetylneuramin-lactose | NeuAc 2→ 3Gal 1→ 4Glc 1 |
| Galactosyl-ceramide | 3Gal 1→ 1′Cer |
| Sulfatide | SO3−→ 3Gal 1→ 1′Cer |
| asialo-GM1 | Gal 1→ 3GalNAc 1→ 4Gal 1→ 4Glc 1→ 1′Cer |
| GM1 | Gal 1→ 3GalNAc 1→ 4Gal(3← 2NeuAc) 1→ 4Glc 1→ 1′Cer |
| GM2 | GalNAc 1→ 4Gal(3← 2NeuAc) 1→ 4Glc 1→ 1′Cer |
| GM3 | NeuAc 2→ 3Gal 1→ 4Glc 1→ 1′Cer |
| GD1b | Gal 1→ 3GalNAc 1→ 4Gal (3← 2NeuAc8← 2NeuAc) 1→ 4Glc 1→ 1′Cer |
| GT1b | NeuAc 2→ 3Gal 1→ 3GalNAc 1→ 4Gal(3← 2NeuAc8← 2NeuAc) 1→ 4Glc 1→ 1′Cer |
Glc, glucose; Gal, galactose; GalNAc, N-acetyl-galactosamine; NeuAc, neuraminic-acid; Cer, ceramide.
a
Ganglioside nomenclature according to Svennerholm (1964).