Table 1. Ranolazine suppresses DADs.

Effect of ranolazine on ACh and high calcium ([Ca²⁺]_o = 5.4 mM)-induced delayed afterdepolarizations (DADs). Summarized are the maximum amplitudes and coupling intervals of the DADs and the concentrations of ranolazine needed to suppress the DADs by ≥ 90%. DADs were elicited by stimulation trains of 20 beats at a BCL of 70 to 200 ms

Exp #	Max DAD Amplitude (mV)	Coupling Interval of DAD (ms)	[Ranolazine] to Suppress DAD (µM)
1	7.2	630	10
2	7.5	610	20
3	5.3	380	10
4	6.4	427	10
5	5.7	448	20