Skip to main content
. Author manuscript; available in PMC: 2008 Aug 17.
Published in final edited form as: Biochemistry. 2006 Jun 20;45(24):7586–7597. doi: 10.1021/bi0603928

Figure 1.

Figure 1

Dose response curves of select FLP-18 peptides. Peptides were applied to Xenopus oocytes expressing NPR-1 215V, and the responses from inward rectifying K+ channels were recorded and normalized to the response of peptide 1 (EMPGVLRF-NH2) at 10-6 M. Filled circles are peptide 1 (EMPGVLRF-NH2) (EC50 = 10-6.80 M), open squares are peptide 5 (SGSGAMPGVLRF-NH2) (EC50 = 10-6.12 M), and open circles are peptide 2 (DFDGAMPGVLRF-NH2) (EC50 = 10-5.28 M). Three measurements at each peptide concentration were obtained and results are shown +/- SEM.