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. Author manuscript; available in PMC: 2009 Jun 23.
Published in final edited form as: Neuroscience. 2008 Mar 29;154(2):482–495. doi: 10.1016/j.neuroscience.2008.03.046

Figure 8. Modulation of PKC system on the effects induced by hypo and hypertonicity.

Figure 8

A. Pre-incubation with PKC antagonists, BIM and staurosporine, significantly reversed the increase of IK by hypotonicity from 34.52±8.58% to 17.48±5.59% (n=12) (unpaired t test, P<0.05) and 15.11±6.17% (n=10) (unpaired t test, P<0.05) respectively. B. Neither BIM nor staurosporine statistically affected the inhibitions of VGPCs by hypertonicity (unpaired t test, P>0.05). In the presence of BIM and staurosporine, IK was inhibited by 37.88±7.38% (n=11) and 35.43±6.01% (n=8), respectively and IA by 25.03±6.12% (n=12) and 27.13±5.05% (n=8), respectively.