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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: J Adolesc Health. 2008 May 19;43(2):115–124. doi: 10.1016/j.jadohealth.2008.02.003

Table 1.

Table 1a. Characteristics of Subjects by Category
Normal Abnormal physical exam Abnormal cycles Abnormal physical exam & abnormal cycles
Group I (N=42) Group II (N=41) Group III (N=15) Group IV (N=22) P value
Demographic Characteristics
Age, mean (SD), yrs 17.4 (2.47) 17.4 (2.48) 17.0 (1.68) 18.0 (2.46) 0.660
Ethnic origin No. (%)
 Hispanic
 Black
 White
 Other
23 (54.8)
14 (33.3)
3 (7.1)
2 (4.8)
25 (61.0)
11 (26.8)
4 (9.8)
1 (2.4)
9 (60.0)
4 (26.7)
1 (6.7)
1 (6.7)
16(72.7)
4 (18.2)
0(0)
2 (9.1)
0.5811
0.6391
0.5291
0.6981
Age at Menarche, median, yrs 11.0 12.0 13.0 11.5 <0.012
Gynecologic Age, median, yrs 5.7 6.7 3.9 6.5 0.0342
Physical Exam Findings
Body Mass Index, mean (SD) kg/m2 23.1 (3.19) 27.6 (9.35) 22.4 (2.98) 32.2 (7.36) <0.013
Overweight (≥95th % ile for age) (%) - 32 - 50 0.1541
Waist Circumference, mean (SD), cm 70.2 (6.49) 77.7 (14.14) 71.2 (7.42) 89.4 (15.86) <0.014
Ferriman Gallwey Score, Median 2 2 2 5.5 <0.015, *
Clitoral Index, Median, mm2 18 26 21 35 <0.016, *
Hirsutism (%) - 24 - 36 0.3161
Acanthosis Nigricans (%) - 54 - 77 0.0661
Acne (%) - 27 - 32 0.6761
Table 1b. Characteristics by Category: Analysis Restricted to Subjects without Overweight and/or Acanthosis Nigricans*
Normal Abnormal physical exam Abnormal cycles Abnormal physical exam & abnormal cycles
Subjects with BMI<95th %ile (n=96)* Group I (N=42) Group II (N=28) Group III (N=15) Group IV (N=11) P value (ANOVA)
Body Mass Index, mean (SD) kg/m2 23.1 (3.2) 23.2 (3.9) 22.4 (3.0) 26.9 (2.7) <0.01a
Waist Circumference, mean (SD), cm 70.2 (6.5) 71.7 (8.2) 71.2 (7.4) 79.0 (8.6) <0.01b
Ferriman Gallwey Score, Median 2 2 2 5 0.03c
Clitoral Index, Median, mm2 18 24 21 30 0.07d
Subjects without Acanthosis Nigricans (n=81)* Group I (N=42) Group II (N=19) Group III (N=15) Group IV (N=5) P value (ANOVA)
Body Mass Index, mean (SD), kg/m2 23.1 (3.2) 24.6 (5.8) 22.4 (3.0) 27.9 (3.1) 0.03e
Waist Circumference, mean (SD), cm 70.2 (6.5) 74.1 (11.1) 71.2 (7.4) 79.9 (10.7) 0.05
Ferriman Gallwey Score, Median 2 3 2 2 0.38d
Clitoral Index, Median, mm2 18 25 21 15 0.23d
Subjects with BMI<95th %ile and no Acanthosis Nigricans (n=75)* Group I (N=42) Group II (N=14) Group III (N=15) Group IV (N=4) P value (ANOVA)
Body Mass Index, mean (SD), kg/m2 23.1 (3.2) 21.9 (3.9) 22.4 (3.0) 27.6 (3.4) 0.02f
Waist Circumference, mean (SD), cm 70.2 (6.5) 68.8 (6.7) 71.2 (7.4) 80.6 (12.2) 0.03g
Ferriman Gallwey Score, Median 2 3 2 2 0.30d
Clitoral Index, Median, mm2 18 25 21 20 0.27d

SD – standard deviation

*

p<0.05 for significantly positive trend from group I to IV by Kendall’s Tau_b and Spearman’s rho.

1

Chi-square

2

Kruskal-Wallis

3

ANOVA, Post-hoc Scheffe (group I vs. II, p=0.03, group I vs. IV, group III vs. IV, p<0.01)

4

ANOVA, Post-hoc Scheffe (group I vs. II, p=0.04, group I vs. IV, group II vs IV, group III vs. IV, p<0.01)

5

Kruskal-Wallis, Mann-Whitney (group IV vs groups I, II, III, p<0.05)

6

Kruskal-Wallis, Mann-Whitney (group I vs II, group III vs IV, p<0.03, group I vs IV, p<0.01,)

SD – standard deviation,

*

Of the 120 subjects, 6 were overweight, 21 had acanthosis nigricans, and 18 were both overweight and had acanthosis nigricans

a

ANOVA, Post-hoc Scheffe (group I vs. IV, p=0.01, group II vs. IV,p=0.02, group III vs. IV, p=0.01).

b

ANOVA, Post-hoc Scheffe (group I vs. IV, p<0.01, group II vs. IV,p=0.05, group III vs. IV, p=0.07).

c

Kruskal-Wallis, Mann-Whitney (group I vs II p=0.05, Group I vs IV, p<0.01, group III vs IV, p=0.07)

d

Kruskal-Wallis.

e

ANOVA, Post-hoc Scheffe (group I vs. IV, p=0.08, group II vs. IV,p=0.06).

f

ANOVA, Post-hoc Scheffe (group I vs. IV, p=0.08, group II vs. IV,p=0.03, group III vs. IV, p=0.05).

g

ANOVA, Post-hoc Scheffe (group I vs. IV, p=0.05, group II vs. IV,p=0.04).