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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: J Adolesc Health. 2008 May 19;43(2):115–124. doi: 10.1016/j.jadohealth.2008.02.003

Table 3.

Receiving Operating Characteristics (ROC) Curve Analysis to Evaluate the Diagnostic Accuracy of Select Biochemical Tests and Clinical Markers for the Diagnosis of Hyperandrogenic Anovulation

Biochemical Test or Clinical Marker Area under the ROC curve 95% Confidence Interval Inflection Point of Greatest Sensitivity and Specificity (sensitivity, specificity)
Testosterone 0.689 0.686–0.923 73.4 (0.632, 0.750)
1/SHBG 0.917 0.852–0.983 1.2 (0.864, 0.854)
FAI 0.887 0.867–0.991 6.0 (0.842, 0.778)
Δ 4A 0.743 0.602–0.884 339 (0.667, 0.805)
LH 0.763 0.630–0.896 6.2 (0.727, 0.707)
LH: FSH Ratio 0.748 0.610–0.887 1.2 (0.818, 0.293)
1/GIR 0.776 0.639–0.913 5.3 (0.818, 0.690)
Clitoral Index 0.782 0.659–0.905 24.5 (0.714, 0.707)
Age at Menarche 0.583 0.425–0.741 11.5 (0.545, 0.548)
Waist Circumference 0.897 0.815–0.979 75.25 (0.864, 0.857)
Waist Circumference* 0.824 0.717–0.931 77.75 (0.786, 0.714)
BMI* 0.839 0.739–0.939 27.0 (0.786, 0.730)
*

ROC curves were generated using redefined physical exam criteria with overweight and acanthosis nigricans removed from prospective physical exam criteria.