Figure 4.
Effect of rEA and varying combinations of IL-2 on survival outcome in hamsters challenged with PTV. Groups of hamsters (n = 10) were dosed i.p. with rEA (100 μg) and IL-2 (38, 12 or 4 μg) alone (A) or in combination (B), 4 h prior to infectious challenge with PTV and on day 3 of the infection. A group of 10 animals was treated with a single i.p. dose of poly(I:C12U) (100 μg) 4 h prior to infectious challenge and served as the positive control. The survival curves for this experiment are presented in two graphs with the placebo data included in both for ease of visualization. **P < 0.01 compared to 0.1% BSA/PBS placebo-treated hamsters (n = 20) by log-rank analysis.