Table 3.
Staining results of metastases compared with primary tumours and concordance scores and discordance scores in 71 normal mucosa, 71 primary tumour (P), 64 nodal metastases (L), and 40 liver metastases (V)
| Positive expression | Concordance (scores) positive/negative | Discordance (scores) (higher:lower/lower:higher) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Proteins | Normal +(%) | Primary +(%) | Nodal +(%) | Liver +(%)* | P/L | P/V | L/V | P/L | P/V | L/V |
| nm23 | 66 (93.0) | 59 (83.1) | 45 (70.3) | 18 (45.0)†† | 32/9 | 5/7 | 7/8 | 21/2 | 27/1 | 14/4 |
| KAI-1 | 68 (95.8) | 53 (74.6)§ | 42 (65.6) | 20 (50)¶ | 22/13 | 6/10 | 16/10 | 26/3 | 22/2 | 6/1 |
| KISS-1 | 68 (95.8) | 53 (74.6)§ | 39 (60.9) | 23 (57.5) | 22/16 | 7/8 | 10/7 | 24/2 | 22/3 | 13/3 |
| P53 | 36 (50.7) | 65 (91.6)** | 58 (90.6) | 36 (90) | 40/4 | 20/3 | 18/4 | 6/14 | 4/13 | 1/10 |
*
+(%): +numbers of positive cases; %: numbers of positive cases/numbers of positive cases and negative cases ×100
†
P = 0.000 (χ2 = 17.478) compared with primary tumours
‡
P = 0.010 (χ2 = 6.604) compared with nodal tumours
§
P = 0.000 (χ2 = 12.574) compared with normal mucosas
¶
P = 0.009 (χ2 = 6.904) compared with primary tumours
**
P = 0.000 (χ2 = 28.839) compared with normal mucosas.