Table 1.
Groups (n) | SH 1 (9) | MI 1 (9) | SH 3 (16) | MI 3 (15) | SH 7 (10) | MI 7 (9) | SH 28 (11) | MI 28 (11) |
---|---|---|---|---|---|---|---|---|
MAP (mmHg) | ||||||||
Initial | 114 ± 4 | 85 ± 6* | 107 ± 3 | 95 ± 6* | 100 ± 6 | 85 ± 6* | 108 ± 3 | 93 ± 5* |
Final | 111 ± 5 | 86 ± 6* | 101 ± 4 | 86 ± 5* | 101 ± 4 | 79 ± 8* | 97 ± 9 | 94 ± 4* |
LVSP (mmHg) | ||||||||
Initial | 132 ± 5 | 104 ± 6* | 126 ± 4 | 117 ± 6* | 123 ± 5 | 103 ± 6* | 127 ± 5 | 112 ± 5* |
Final | 133 ± 7 | 107 ± 6* | 125 ± 5 | 113 ± 5* | 128 ± 4 | 105 ± 8* | 127 ± 9 | 112 ± 4* |
LVEDP (mmHg) | ||||||||
Initial | 5.0 ± 0.8 | 12.6 ± 1.3* | 5.4 ± 0.5 | 11.2 ± 1.3* | 5.5 ± 0.7 | 10.1 ± 1.4* | 5.5 ± 0.4 | 10.2 ± 1.2* |
Final | 5.3 ± 0.8 | 10.6 ± 1.0* | 4.9 ± 0.5 | 9.1 ± 1.5* | 6.0 ± 0.8 | 13.7 ± 3.4* | 7.3 ± 0.5 | 10.6 ± 2.1* |
CDP (mmHg) | ||||||||
Initial | 109 ± 4 | 72 ± 7* | 102 ± 4 | 83 ± 7* | 95 ± 6 | 75 ± 7* | 102 ± 3 | 83 ± 6* |
Final | 106 ± 4 | 75 ± 5* | 96 ± 4 | 78 ± 4* | 95 ± 4 | 65 ± 9* | 90 ± 9 | 84 ± 5* |
+dP/dt (mmHg/s) | ||||||||
Initial | 8310 ± 570 | 5728 ± 336* | 7757 ± 411 | 6557 ± 518* | 7451 ± 718 | 5374 ± 376* | 8045 ± 448 | 6099 ± 406* |
Final | 7730 ± 602 | 5907 ± 382* | 7432 ± 384 | 6673 ± 410* | 7574 ± 305 | 4973 ± 639* | 7002 ± 665 | 6065 ± 310* |
−dP/dt (mmHg/s) | ||||||||
Initial | 6648 ± 505 | 3248 ± 300* | 6269 ± 405 | 4112 ± 373* | 5446 ± 518 | 3316 ± 289* | 6113 ± 364 | 3822 ± 384* |
Final | 6840 ± 376 | 4858 ± 303*† | 6524 ± 259 | 4775 ± 264* | 6750 ± 665 | 4045 ± 555*† | 6057 ± 818 | 5184 ± 512† |
SH, sham group; MI, myocardial infarction group; MAP, mean arterial pressure; LVSP, left ventricular systolic pressure; LVEDP, left ventricular end-diastolic pressure; CDP, coronary driving pressure; +dP/dt, maximum positive first derivative of left ventricular pressure; −dP/dt, maximum negative first derivative of left ventricular pressure.
P < 0.05 vs. SH.
P < 0.05 final vs. initial.