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. 2007 Oct;88(5):361–376. doi: 10.1111/j.1365-2613.2007.00543.x

Figure 1.

Figure 1

Histology of the liver from a rat treated with carbon tetrachloride (CCl4) twice a week for 6 weeks and sampled at 6 weeks. (a) Liver from a control rat to show the normal arrangement and appearance of hepatocytes. (b) Centrilobular region in the liver of a rat treated with CCl4 at 0.36 ml/kg twice weekly for 6 weeks showing diffuse, marked, hepatocellular vacuolation and degeneration, with necrotic cells. Original magnification of images; ×400 (haematoxylin and eosin).