Figure 2.

Vascular endothelial growth factor (VEGF) plasma levels during foetal development expressed in pg of VEGF/ml (mean ± SD). Gradual increase of VEGF plasma levels throughout development in control subjects. A prominent increase at the 15th gestational day is observed, both in control and in vitamin A treated foetuses. In the last gestational day, VEGF plasma levels are higher in control foetuses, reaching a significant statistical difference. At the day of birth, however, control and treated animals display similar VEGF plasma levels. **P < 0.05 (vs. control); *P < 0.0001 (vs. control).