Table 1.
Genotype and age differences in small intestinal villi and crypt measurements
| VNDR | CNDR | CVR | ||||
|---|---|---|---|---|---|---|
| Mice | 12 week | 15 week | 12 week | 15 week | 12 week | 15 week |
| Duodenum | ||||||
| ApcMin/+ | 17.45 ± 0.98 | 14.09 ± 0.60 | 4.30 ± 0.30 | 3.21 ± 0.14 | 0.24 ± 0.01 | 0.24 ± 0.01 |
| C57BL/6 | 17.33 ± 0.94 | 14.27 ± 0.43 | 4.72 ± 0.28 | 3.39 ± 0.18 | 0.24 ± 0.01 | 0.23 ± 0.02 |
| Jejunum | ||||||
| ApcMin/+ | 10.49 ± 1.34 | 8.73 ± 0.39 | 5.06 ± 0.54 | 3.69 ± 0.13 | 0.40 ± 0.02 | 0.41 ± 0.03 |
| C57BL/6 | 10.37 ± 1.19 | 9.18 ± 0.37 | 5.39 ± 0.32 | 3.68 ± 0.18 | 0.41 ± 0.04 | 0.43 ± 0.03 |
| Ileum | ||||||
| ApcMin/+ | 7.57 ± 0.59* | 7.43 ± 0.27† | 4.87 ± 0.37 | 4.42 ± 0.15 | 0.64 ± 0.05 | 0.65 ± 0.03 |
| C57BL/6 | 6.24 ± 0.52* | 6.28 ± 0.43† | 4.48 ± 0.26 | 3.97 ± 0.17 | 0.58 ± 0.02 | 0.60 ± 0.02 |
CNDR, crypt depth/neck diameter of crypt; CVR, ratio of crypt depth/villi length; VNDR, ratio of villi length/neck diameter of crypt.
*
Significant genotype difference, P < 0.05.