Figure 6.
Rat liver from day 35 at high dose NNM feeding. Alpha-1-fetoprotein (AFP) immunoreactive ductular epithelial cells (oval cells) in transition towards hepatocytes giving rise to a nodule of hyperplastic appearance; note strong immunoexpression of AFP in both small oval cells and cells with the appearance of small intermediate-sized hepatocytes (original magnification ×160, haematoxylin counterstain).