Table 3.
Quantification of the features of cell damage in the skin of Albino rats
| Features of cell damage | Non-irradiated skin | X-ray-irradiated skin | XRI skin with melatonin pretreatment | P-value |
|---|---|---|---|---|
| Apoptotic changes | 1.2 ± 0.3 | 5.0 ± 0.7 | 2.4 ± 0.5 | 0.001 |
| Cytoplasmic vacoulization | 2.2 ± 0.9 | 8.2 ± 1.3 | 4 ± 0.9 | 0.004 |
| Birbecks granules | 4.8 ± 0.9 | 7.6 ± 0.9 | 4.8 ± 1.1 | 0.030 |
| Non-swollen mitochondria | 6.6 ± 0.9 | 1.6 ± 0.7 | 4.4 ± 0.5 | 0.002 |
| Swollen mitochondria | 0.0 ± 0.0 | 5 ± 0.8 | 1.8 ± 0.4 | 0.000 |
| Density of the lipid droplets | ||||
| Dense | 21 ± 2.3 | 2.0 ± 0.7 | 22 ± 1.4 | 0.000 |
| Less dense | 4.4 ± 0.9 | 22 ± 1.07 | 2.0 ± 0.7 | 0.000 |
P-values refer to XRI vs. XRI skin with melatonin pretreatment.