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. 2004 Dec;85(6):365–371. doi: 10.1111/j.0959-9673.2004.00405.x

Table 1.

Effect of MG132 on protein and amino acid metabolism

Muscle Control MG132
Proteolysis (nmol tyrosine/g wet weight/h) SOL (n = 8) 82 ± 4 39 ± 2*
EDL (n = 8) 75 ± 2 31 ± 1*
Protein synthesis (nmol leucine/g of protein/h) SOL (n = 9) 1393 ± 67 1095 ± 124**
EDL (n = 10) 731 ± 49 658 ± 55**
Leucine oxidation (nmol leucine/g wet weight/h) SOL (n = 10) 74.3 ± 6.8 67.7 ± 6.4
EDL (n = 10) 68.3 ± 4.5 57.4 ± 6.2***

Mean ± SEM. Paired t-test

*

P < 0.001

**

P < 0.01

***

P < 0.05. EDL, extensor digitorum longus; SOL, soleus.