Table 2.
Sham (n ≥ 8) | CLP (n ≥ 11) | Sham (n ≥ 8) | CLP (n ≥ 11) | ||
---|---|---|---|---|---|
Thrombocytes (*109/l) | 1052.5 ± 54.7 | 467 ± 53.7* | Alanine aminotransferase (µkat/l) | 0.4 ± 0.01 | 1.3 ± 0.1* |
Haematocrit | 0.34 ± 0.01 | 0.29 ± 0.01** | Aspartate aminotransferase (µkat/l) | 1.9 ± 0.1 | 3.9 ± 0.4* |
Haemoglobin (g/l) | 106.8 ± 2.5 | 89.1 ± 5.2** | Spleen weight (mg/g of body weight) | 3.3 ± 0.2 | 4.1 ± 0.3** |
Na+ (mmol/l) | 134.5 ± 1.4 | 128.1 ± 0.9* | Dry-to-wet weight ratio of the spleen | 0.228 ± 0.003 | 0.206 ± 0.006** |
K+ (mmol/l) | 3.4 ± 0.1 | 3.8 ± 0.1** | Dry-to-wet weight ratio of the liver | 0.268 ± 0.005 | 0.246 ± 0.002** |
Cl– (mmol/l) | 98.1 ± 1.4 | 95 ± 1.0** | Dry-to-wet weight ratio of the left kidney | 0.224 ± 0.002 | 0.213 ± 0.003** |
Lactate dehydrogenase (µkat/l) | 2.6 ± 0.5 | 8.7 ± 1.6** | Dry-to-wet weight ratio of the right kidney | 0.224 ± 0.002 | 0.212 ± 0.004** |
Mean ± SEM. Two-sample t-test
P < 0.001 vs. control (sham-operated)
P < 0.05 vs. control (sham-operated). CLP, caecal ligation and puncture