Table 3.

Protein and amino acid metabolism – changes in muscles of rats made septic by means of caecal ligation and puncture (CLP)

	Muscle	Sham	CLP
Proteolysis (nmol tyrosine/g wet weight/h)	SOL (n ≥ 9)	78.8 ± 2.3	98.2 ± 5.8*
	EDL (n ≥ 10)	73.8 ± 1.7	93.7 ± 5.7*
Protein synthesis (nmol leucine/g of protein/h)	SOL (n = 10)	1350 ± 74	1142 ± 72*
	EDL (n = 11)	699 ± 55	529 ± 53*
Leucine oxidation (nmol leucine/g wet weight/h)	SOL (n = 11)	71 ± 7	127 ± 10**
	EDL (n = 11)	68 ± 4	132 ± 9**

Mean ± SEM. Two-sample t-test

^*P < 0.05vs. control (sham-operated)

^**P < 0.001 vs. control (sham-operated). EDL, extensor digitorum longus; SOL, soleus.