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Infiltration of mononuclear cells at 12 d. p.i. in and around a pancreatic islet of the mouse treated with empty plasmid (10 µg) (a, and b; higher magnification of arrow in a), whereas cellular infiltration in and around islets in the mouse treated with the pIL-4 (10 µg) is prominently reduced (c, and d; higher magnification of arrow in c). Representative histological changes are shown. HE. ×50 (a and c), ×200 (b and d).
