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. 2003 Jun;84(3):107–113. doi: 10.1046/j.1365-2613.2003.00342.x

Figure 2.

Figure 2

(a) 129(S)V+/+ grafts implanted into Balb/c mice: mucosal rejection process at intervals to 9 days post implantation. Mucosal injury varied from none (‘normal’) to complete destruction (‘submucosa’) (Ferguson & Parrott 1973). Intermediate grades ‘L +, L ++, and flat’ indicated lamina propria lymphocytic infiltration, reduction in villous height, and subtotal villous atrophy with crypt hyperplasia, respectively. (b) 129(S)V−/− grafts implanted into Balb/c mice: mucosal rejection process at 5 and 9 days post implantation. Histological grading as described by Ferguson & Parrott (1973). (c) 129(S)V−/− grafts implanted into 129SV−/− mice: mucosal rejection process at 5 and 9 days post implantation. Histological grading as described by Ferguson & Parrott (1973).