Table 2.
Quantitative rtPCR analysis of cytokine mRNA expression in graft tissue at 9 days post implantation
| Graft/Recipient | n | IFN-γ | TNFα | IL-4 |
|---|---|---|---|---|
| 129SV+/+ | 5 | 64 000 | 217 960 | 0 |
| →Balb/c | (0–204 559) | (44 207−1.53 × 106) | (0–131 793) | |
| 129SV−/− | 7 | 42012 | 5584 | 0 |
| →Balb/c | (0–0.5 × 106) | (0–335 378) | (0–27 476) | |
| 129SV−/− | 8 | 0 | 0 | 0 |
| →129SV−/− | (0–3752) | (0–2064) | (0–0) | |
| NS | P = 0.02 | NS |
Results expressed as number of cytokine RNA transcripts per µg total sample RNA: median (inter-quartile range). Statistics: Cuzick's test for trend applied to the three study groups. NS = not significant.