. Author manuscript; available in PMC: 2009 Jul 1.

Published in final edited form as: Epilepsy Behav. 2008 Mar 11;13(1):62–69. doi: 10.1016/j.yebeh.2008.02.008

Table 2.

Effects of PTB on SE, latency to seizure cessation, and mortality as a function of age.

Age	SE	PTB dose mg/kg	n	SE Stopped	Dose trend for SE stopped(p)	Min. to SE stop	Dose trend for Min. to SE stop(p)	Mortality	Dose Trend for mortality(p)
P9	KA	40	10	0 (0%)	-	NA	-	0 (0%)	0.000023 *
	KA	45	8	0 (0%)	-	NA	-	8 (100%)	0.000023 *
	Li-Pilo	40	6	0 (0%)	-	NA	-	6 (100%)	-
	Li-Pilo	45	9	0 (0%)	-	NA	-	9 (100%)	-
P15	KA	30	5	0 (0%)	0.0000031 *	NA	0.11	0 (0%)	0.34
		40	6	1 (17%)		3.5		1 (17%)
		50	13	13 (100%)		2.5 ± 0.2		3 (23%)
	Li-Pilo	30	4	0 (0%)	0.00017 *	NA	0.47	0 (0%)	0.00017 *
		40	6	3 (50%)		5.9 ± 0.2		6 (100%)
		50	11	11 (100%)		5.0 ± 0.6		11 (100%)
P21	KA	30	6	0 (0%)	0.000022 *	NA	0.47	0 (0%)	-
		40	11	6 (55%)		13.0 ± 0.6		0 (0%)
		50	11	11 (100%)		12.5± 0.3		0 (0%)
	Li-Pilo	30	6	1 (17%)	0.0033 *	NA	0.04 *	1 (17%)	0.013 *
		40	5	4 (80%)		7.5 ± 0.3		3 (60%)
		50	11	10 (91%)		6.9 ± 0.3		9 (82%)

NA – not applicable