Figure 1.
Prognostic relevance of hTERT mRNA expression, analyzed with multivariate Cox proportional hazard regression model for overall survival for 56 PDAC patients (UICC stages I–IV, R0–2 resection), adjusted for tumor stage, type of tumor resection, and patients' age. Cutoffs for expression of hTERT were the mean value (61 ag) and undetectable mRNA levels (0.00 ag): >61 ag (high); >0.00 to ≤61 ag (low), and 0.00 ag mRNA (not detectable) standardized to HPRT transcript levels.