Figure 5. Exogenous superkiller TRAIL does not cause deleterious effects on immune cell numbers or function.

PBLs from HIV infected subjects were cultured with skTRAIL or BSA and analyzed for percent of T, B and NK cells (A, top panel), and percent CD4+ and CD8+ memory and naïve T cells (A, bottom panel) by flow cytometry. Cultured PBLs were also analyzed for CD4 and CD8 recall responses by ELISPOT (B).