Figure 9.

Quantification of CK-MB activity in plasma taken from perforin (+/+) (a) and (−/−) (b) mice before and after 8, 15 and 22 days of infection. Solid lines represent the median of individual groups and the dots indicate individual mice values. (ND) The corresponding CK-MB dosages were not included because most of the perforin (−/−) mice died before the 21st dpi. (*) Indicates statistically significant differences (P < 0.05) of perforin (−/−) mice as compared to perforin (+/+) mice. (#) Indicates statistically significant differences (P < 0.05) of infected perforin (−/−) mice on the 15th dpi as compared with control (−/−) mice.