Table 2.
Score and percentage (morphometric studies, MS) of tubulointerstitial lesions (TIL) and scores for α- SM-Actin, fibronectin, and TGF-β staining in cortical tubulointerstitium and number of cells ED1 positive per grid field of renal cortex measuring 0.245 mm2 for control rats (C) and for rats killed 5 (G-5 days), 30 (G-30 days) and 60 days (G-60 days) after glycerol (G) injection
| Groups | C (N=6) | G-5days (N=8) | G-30days (N=8) | G-60days (N=9) |
|---|---|---|---|---|
| TIL, score | 0.10±0.10 | 3.75±0.16*** | 1.94±0.24***### | 2.00±0.24***### |
| %TIL, MS | 0.63±0.28 | 13.82±2.74* | 17.44±2.70** | |
| α-SM-actin | 0.025±0.01 | 1.48±0.14*** | 0.33±0.07*### | 0.27±0.05### |
| Fibronectin | 0.38±0.04 | 1.31±0.03*** | 0.97±0.13**# | 1.11±0.08*** |
| ED1+cells | 5.05±1.20 | 44.76±4.67*** | 19.00±3.45*### | 18.42±2.08*### |
| TGF-β | 0.66±0.07 | 1.52±0.04*** | 1.12±0.03***### | 1.14±0.05***### |
Data are expressed as mean±SEM
*
P < 0.05 vs. control
**
P < 0.01 vs. control
***
P < 0.001 vs. control
#
P < 0.05 vs. G-5days
##
P < 0.01 vs. G-5days
###
P < 0.001 vs. G-5days.