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. 2002 Oct;83(5):225–238. doi: 10.1046/j.1365-2613.2003.00232.x

Table 4.

Counts (×107) of myeloid, erythroid and lymphoid cells, and the myeloid : erythroid (M : E) ratio in femoral marrow smears of control and CAPS-treated guinea pigs; animals were treated with CAPS at 825 mg/kg, or vehicle solution daily for 16 days, and sampled at 1, 12, 28 and 63 days after the final dose

Day of sampling

Day 1 Day 12 Day 28 Day 63




Control CAPS Control CAPS Control CAPS Control CAPS
Myeloid 6.73 (1.95) 3.35 (1.03)* 6.42 (2.47) 3.61 (1.16) 4.99 (1.07) 6.40 (2.88) 7.05 (1.16) 5.66 (1.19)
Erythroid 7.72 (0.94) 0.04 (0.02)** 6.37 (2.16) 6.64 (1.96) 5.06 (1.51) 5.82 (3.45) 5.44 (1.27) 3.90 (1.29)
Lymphoid 7.13 (1.53) 1.91 (0.80)** 5.52 (0.42) 3.69 (1.20)* 4.46 (1.02) 5.54 (3.20) 4.09 (0.33) 3.60 (1.19)
Other 0.79 (0.23) 0.95 (0.57) 0.61 (0.23) 0.48 (0.38) 0.31 (0.17) 0.28 (0.16) 0.23 (0.14) 0.24 (0.19)
M:E ratio 0.86 (0.19) 79.61 (26.50)** 1.01 (0.13) 0.57 (0.24)** 1.06 (0.48) 1.22 (0.46) 1.35 (0.43) 1.53 (0.45)

200 cells in the femoral marrow smears were differentiated by eye and the absolute number of cells in each lineage calculated from the FNCC of the opposing femoral marrow flush. Values are means, SD in parentheses. All other information as Tables 1 and 3.