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. 2001 Jun;82(3):193–200. doi: 10.1046/j.1365-2613.2001.iep0082-0193-x

Figure 5.

Figure 5

Effect of soluble hyaluronan (sHA) on adhesion, haptotaxis, CD44 expression and proliferation of Hs578T and MDA-MB-231cells. Cells were grown in regular culture medium (RCM) or in RCM containing soluble hyaluronan (sHA) for 3 days. (a): Hs578T cells that were grown with sHA are more adhesive to HA, less motile towards HA and express more CD44 molecules on their membrane. No differences in proliferation are observed. (b): MDA-MB-231 cells that were grown with sHA express more CD44 molecules on the cell membrane and are less motile towards hyaluronan. Proliferation rate is the same.