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. 1999 Aug;80(4):189–196. doi: 10.1046/j.1365-2613.1999.00114.x

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© 1999 Blackwell Science Ltd

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CT-1 was cultured with cardiac myocytes for 30min under normoxic conditions in the absence () and presence of 50μm PD98059 (▪) or 10μm SB203580 (). No treatment (□). The inhibitors were added to the cells 30 min before the addition of CT-1. The CT-1 and inhibitors were removed from the cells which were then exposed to a 6-h simulated lethal hypoxic/ischaemic stress. The cells were harvested and cell death was assessed by trypan blue exclusion. *P < 0.05.

Inline graphic — CT-1 was cultured with cardiac myocytes for 30min under normoxic conditions in the absence () and presence of 50μm PD98059 (▪) or 10μm SB203580 (). No treatment (□). The inhibitors were added to the cells 30 min before the addition of CT-1. The CT-1 and inhibitors were removed from the cells which were then exposed to a 6-h simulated lethal hypoxic/ischaemic stress. The cells were harvested and cell death was assessed by trypan blue exclusion. *P < 0.05.