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Splenic changes in mice infected with T. cruzi and treated with Benznidazole: a) hyperplastic germinal centres, with focal area of necrosis, and absence of parasites; H&E, 250X; b) focal area of cell necrosis and apoptosis in the red pulp; one macrophage with vacuolated cytoplasm (arrow head), free from parasites; H&E, 400X.
