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. 1999 Dec;80(6):305–315. doi: 10.1046/j.1365-2613.1999.00128.x

Figure 4.

Figure 4

Representation of the IP3 receptor which regulates calcium release from endoplasmic reticulum. FKBP anchors calcineurin to the IP3 receptor complexes and calcium flux is regulated by a mechanism involving calcineurin phosphatase activity which is disrupted by FK 506.