Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The proteolytic activity of KLK6 serves as a feed-back inhibitory mechanism via internal hydrolysis after Arg76. By comparison, the ability of KLK6 to function as a feed-back activator of pro-KLK6 appears substantially less significant, and distinct activating proteases such as plasmin or KLK5 are much more effective activators of pro-KLK6.
