Table 1.
Total (n = 512) | Judged bupropion (n = 253) | Judged placebo (n = 167) | Judged uncertain (n = 66) | |
---|---|---|---|---|
Age, mean (SD) | 44.7 (11.2) | 45.2 (12.0) | 43.9 (9.7) | 44.6 (11.7) |
Female (n, %) | 351(68.6%) | 170 (67.2%) | 115 (68.9%) | 66 (71.7%) |
Weight (kg), mean (SD) | 183.9 (46.6) | 182.5 (47.4) | 186.8 (47.4) | 82.8 (19.5) |
≤High school graduate, n (%) | 248 (48.4%) | 120 (47.4%) | 79 (47.3%) | 49 (53.3%) |
aMonthly income <$1,800, n (%) | 276 (54.8%) | 139 (55.9%)a | 74 (45.1%)a | 63 (69.2%)a |
Married or cohabitating, n (%) | 193 (37.7%) | 95 (37.6%)b | 73 (43.7%)b | 25 (27.2%)b |
Menthol, n (%) | 396 (77.3%) | 193 (76.3%) | 135 (80.8%) | 68 (73.9%) |
CPD, mean (SD) | 19.0 (8.1) | 19.0 (8.1) | 19.3 (7.8) | 18.8 (8.3) |
bSalivary cotinine (ng/ml), mean (SD) | 288.9 (144.2) | 277.0 (137.5)c | 311.4 (150.7)c | 280.3 (147.1)c |
FTND, mean (SD) | 4.6 (2.0) | 4.5 (2.0) | 4.5 (2.1) | 4.8 (2.0) |
Previous quits, mean (SD) | 2.5 (4.9) | 2.7 (5.0) | 2.4 (5.4) | 2.0 (3.1) |
Previous use of sustained-release bupropion, n (%) | 40 (7.8%) | 18 (7.1%) | 10 (6.0%) | 12 (13.0%) |
ap < 0.001;
bp = 0.032;
cp < 0.047
CPD = cigarettes per day
FTND = Fagerstrom Test for Nicotine Dependence score33