. Author manuscript; available in PMC: 2009 Jan 1.

Published in final edited form as: J Natl Cancer Inst Monogr. 2008;(39):64–68. doi: 10.1093/jncimonographs/lgn014

Table 1.

NUP98 translocations associated with hematologic malignancy

Translocation	Partner Gene	Homeodomain?	Disease
t(7;11)(p15;p15)	HOXA9, 11, 13	Yes	MDS, AML, CML
t(11;12)(p15:q13)	HOXC11,13	Yes	MDS, AML
t(2;11)(q31;p15)	HOXD9, 11, 13	Yes	MDS, AML, CML
t(1;11)(q23;p15)	PMX1(PRRX1)	Yes	MDS, AML
t(9;11)(q34;p15)	PRRX2	Yes	MDS, AML
t(4;11)(q21;p15)	RAP1GDS1	No	pre-T LBL
t(11;20)(p15;q11)	TOP1	No	MDS, AML
t(9;11)(p22;p15)	LEDGF	No	AML
t(5;11)(q35;p15)	NSD1	No	AML
t(8;11)(p11;p15)	NSD3	No	AML
t(10;11)(q25;p15)	ADD3	No	pre-T LBL
inv11(p15q22)	DDX10	No	MDS, AML
t(6;11)(q24;p15)	C6orf80	No	AMKL, pre-T LBL
t(3;11)(p24;p15)	TOP2B	No	AML
t(11;21;12)(p15;p13;p13)	JAR1D1A	No	AMKL