Subjects (n=206) were randomized for six months to inactivity (nmen= 12, nwomen HRT−=10; nwomen HRT+=5) or one of three aerobic exercise training groups: Low-Amount Moderate Intensity (Low-Mod; nmen= 30, nwomen HRT−=11; nwomen HRT+=16); Low Amount-Vigorous Intensity (Low-Vig; nmen= 33, nwomen HRT−=15; nwomen HRT+=10); High-Amount Vigorous Intensity (High-Vig; nmen= 38, nwomen HRT−=11; nwomen HRT+=15)
A. Change in insulin sensitivity by group and gender was assessed with a two-way analysis of variance (P<0.71). Black bars depict men, and white bars depict women (HRT− and HRT+ combined).
B. Change in insulin sensitivity by group and hormone therapy use was assessed with a two-way analysis of variance. Black bars depict men; white bars with diagonal lines depict HRT− women; and white bars with dots depict HRT+ women. Both group (P<0.005) and HRT use (P<0.005) were independently related to change in insulin sensitivity. Error bars represent standard error.