TABLE 4.

Mean ± SD and (Percentage of Control Values) for the Volumes of Cell Body, Nucleus, and Nucleolus in the 4 Groups

	Diagnosis	Cell Body	Nucleus	Nucleolus	Neurons
CA1	AD	2,000.7 ± 881.1 (−29.4%)	414.9 ± 124.9 (−30.7%)	3.2 ± 1.6 (−50.0%)	205.4
	MCI	2,648.5 ± 1,197.0 (−6.5%)	520.2 ± 191.2 (−13.1%)	4.8 ± 2.4 (−25.6%)	205.6
	ASYMAD	4,215.4 ± 700.7 (+48.7%)	780.9 ± 231.3 (+30.4%)	10.4 ± 1.7 (+58.6%)	203.8
	C	2,834.07 ± 576.9	598.8 ± 79.3	6.5 ± 2.1	207
ACG	AD	1,159.9 ± 356.8 (−7.7%)	294.3 ± 65.44 (−0.8%)	2.2 ± 0.7 (−2.27%)	207.5
	MCI	1,488.5 ± 216.3 (+18.4%)	360.8 ± 86.22 (+21.5%)	2.9 ± 1.2 (+23.3%)	204.4
	ASYMAD	1,804.4 ± 413.2 (+43.5%)	461.7 ± 128.6 (+55.5%)	5.0 ± 2.3 (+109.2%)	210.2
	C	1,256.7 ± 258.6	296.8 ± 38.17	2.4 ± 0.7	207.2
PCG	AD	1,062.4 ± 415.3 (−7.1%)	298.5 ± 72.7 (+5.5%)	1.7 ± 0.4 (−0.9%)	216.6
	MCI	1,396.6 ± 397.4 (+22.0%)	368.6 ± 91.2 (+30.2%)	2.4 ± 0.8 (+42.2%)	218.0
	ASYMAD	1,402.2 ± 540.6 (+22.5%)	357.3 ± 103.4 (+26.2%)	2.8 ± 1.9 (+63.4%)	212.9
	C	1,144.2 ± 423.2	282.9 ± 82.7	1.7 ± 0.4	207.8
PVC	AD	641.9 ± 158.1 (+29.9%)	219.3 ± 40.8 (+31.3%)	1.0 ± 0.5 (+44.7%)	209.4
	MCI	836.2 ± 280.9 (+69.2%)	262.2 ± 65.6 (+57.1%)	1.2 ± 0.4 (+68.9%)	209.5
	ASYMAD	680.7 ± 152.3 (+37.7%)	242.7 ± 51.9 (+45.4%)	1.1 ± 0.8 (+50.7%)	211.4
	C	494.0 ± 170.5	166.8 ± 47.1	0.7 ± 0.2	208.3

Mean ± SD values and percentages of control values for the cell body, nuclear, and nucleolar volumes in each group for each region: CA1, ACG, PCG, and PVC. Number of neurons is the mean number of neurons measured for each category. Significant differences relative to the control group are in bold (p < 0.01).

AD, Alzheimer disease; ACG, anterior cingulate gyrus; ASYMAD, asymptomatic AD; CA1, CA1 of hippocampus; MCI, mild cognitive improvement; PCG, cingulate gyrus; PVC, primary visual cortex