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Plasma samples from 25 patients with systemic amyloidosis (average age, 52 ± 11 years, 36% male) and of 40 healthy controls (average age, 49.4 ± 7.3 years, 37.5% male) were tested for levels of FXIIa by ELISA. Patients with systemic amyloidosis had significantly elevated levels of FXIIa, as compared by 2-tailed Student’s t test.
