Table 2.

Adjusted odds ratio (OR) and 95% CI of prevalent diabetes by category of six BFRs (n = 1,367)^*

Analyte	Not detectable	Detectable				P trend‡	P quadratic
		<25th†	25th to <50th	50th to <75th	≥75th
PBB-153
Median serum concentration (ng/g of lipid)	—	1.2	2.3	3.8	13.1
Cases/n	11/166	16/306	39/303	41/292	49/300
Adjusted OR (95% CI)	Referent	0.7 (0.3–1.6)	1.4 (0.7–3.0)	1.6 (0.8–3.5)	1.9 (0.9–4.0)	<0.01	0.88
PBDE-28
Median serum concentration (ng/g of lipid)	—	0.7	1.2	2.0	5.4
Cases/n	37/279	19/296	32/262	31/259	37/271
Adjusted OR (95% CI)	Referent	0.5 (0.3–1.0)	1.2 (0.7–2.0)	0.9 (0.5–1.6)	0.8 (0.5–1.4)	0.93	0.97
PBDE-47
Median serum concentration (ng/g of lipid)	—	6.5	13.7	28.2	73.3
Cases/n	2/36	43/333	34/333	40/332	37/333
Adjusted OR (95% CI)	Referent	3.4 (0.8–15.7)	2.9 (0.6–13.5)	3.8 (0.8–17.4)	2.7 (0.6–12.5)	1.00	0.16
PBDE-99
Median serum concentration (ng/g of lipid)	—	3.1	5.3	9.2	26.9
Cases/n	45/456	37/231	25/222	22/230	27/228
Adjusted OR (95% CI)	Referent	2.0 (1.2–3.2)	1.5 (0.9–2.6)	1.2 (0.7–2.2)	1.3 (0.7–2.2)	0.57	0.06
PBDE-100
Median serum concentration (ng/g of lipid)	—	1.4	2.8	5.6	16.8
Cases/n	10/94	37/330	37/305	35/322	37/316
Adjusted OR (95% CI)	Referent	1.3 (0.6–2.8)	1.6 (0.7–3.5)	1.6 (0.7–3.5)	1.4 (0.6–3.0)	0.50	0.20
PBDE-153
Median serum concentration (ng/g of lipid)	—	1.9	3.6	6.6	24.6
Cases/n	9/101	34/317	40/314	42/316	31/319
Adjusted OR (95% CI)	Referent	1.6 (0.7–3.6)	2.6 (1.2–5.8)	2.7 (1.2–6.0)	1.8 (0.8–4.0)	0.15	<0.01

^*Adjusted for age, sex, race, poverty income ratio, and BMI.

^†Displayed is the median serum concentration in each category.

^‡P trend was calculated without a quadratic term in the model, while P quadratic was calculated including the linear term.