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. 2008 Apr;4(2):389–403. doi: 10.2147/ndt.s6985

Table 2.

Most common medication treatment options for adult ADHD

First line agents Duration of action Start dose Titration schedule Maximum dose
OROS
Methylphenidate HCL
(Concerta)
12 h 18 mg qama ↑18 mg every 7 days 108 mg/day
Long-acting MPH
(Ritalin LA)
8–12 10 mg qam ↑10 mg every 7 days 80 mg/day
Controlled release
Methylphenidate
(Biphentin)
10–12 h 10 mg qam ↑10 mg every 7 days 80 mg/day
Mixed Amphetamine salts XR 12 h 5 mg qam ↑ 5 mg every 7 days 60 mg/day
(Adderall XRc)
Atomoxetine
(Strattera)
24 h 0.5 mg/kg/day ↑ 0.8 mg/kg/day for 10 days, then 1.2 mg/kg/day 100 mg/day
Second line agents
Methylphenidate HCL
(Ritalin)
3–5 h 10 mg qam and qnoonb ↑10 mg every 7 days 100 mg/day
Dextroamphetamine
(Dexedrine)
4–5 h 5 mg qam and qnoon ↑ 5 mg every 7 days 60 mg/day
Dextroamphetamine
Spansule
6–8 h 10 mg qam ↑ 5 mg every 7 days 60 mg/day
(Dexedrine spansule)
a

qam – every morning.

b

qnoon – at noon.

c

Adderall XR – Adderall extended release.