Table 2.
Characteristics of the 66 patients with ESRD as a function of AoC status
| Variable | AoC Negative(n = 18) | AoC Positive(n = 48) | P |
|---|---|---|---|
| Age (yr; mean ± SEM) | 32.80 ± 2.50 | 53.60 ± 1.40 | <0.00010 |
| Aortic PWV (m/s; mean ± SEM) | 8.48 ± 0.38 | 11.63 ± 0.35 | <0.00010 |
| Smoking (pack-years; median [95% CI]) | 0.00 (0.00 to 5.00) | 5.00 (1.00 to 15.00) | <0.01000 |
| Vintage (mo; mean ± SEM) | 59.00 ± 7.90 | 94.00 ± 9.10 | 0.01000 |
| SBP (mmHg; mean ± SEM) | 151.00 ± 6.20 | 158.00 ± 3.10 | NS |
| DBP (mmHg; mean ± SEM) | 86.00 ± 3.80 | 86.00 ± 1.80 | NS |
| Total cholesterol (mmol/L; mean ± SEM) | 4.87 ± 0.30 | 5.18 ± 0.16 | NS |
| Serum albumin (g/L; mean ± SEM) | 40.80 ± 0.40 | 37.90 ± 0.30 | <0.00010 |
| CRP (mg/L) | 2.00 (1.00 to 3.00) | 8.00 (7.00 to 10.00) | <0.00010 |
| Serum Ca (mmol/L; mean ± SEM) | 2.40 ± 0.04 | 2.43 ± 0.02 | NS |
| Ionized Ca (mmol/L; mean ± SEM) | 1.23 ± 0.01 | 1.21 ± 0.01 | NS |
| Serum PO4 (mmol/L; mean ± SEM) | 1.81 ± 0.06 | 2.06 ± 0.06 | <0.01000 |
| Ca*PO4 (mmol2/L2; mean ± SEM) | 4.35 ± 0.17 | 5.00 ± 0.15 | <0.01000 |
| PTH (pg/ml; median [95% CI]) | 411.00 (229.00 to 670.00) | 206.00 (160.00 to 291.00) | <0.00001 |
| Serum Al (μ mol/L; mean ± SEM) | 0.96 ± 0.13 | 1.62 ± 0.14 | <0.01000 |
| Deferoxamine test (ΔAl μ mol/L; mean ± SEM) | 1.48 ± 0.26 | 2.70 ± 0.24 | <0.01000 |
| CaCO3 (g of elemental Ca/d; mean ± SEM) | 1.270 ± 0.300 | 1.900 ± 0.132 | 0.02000 |
| 1α-OH-D3 (μ g/wk; median [95% CI]) | 0.25 (0.00 to 0.50) | 0.00 (0.00 to 0.25) | NS |
| Resorption surfaces (%; median [95% CI]) | 2.56 (1.71 to 3.85) | 0.68 (0.27 to 1.40) | <0.00100 |
| Osteoclasts/mm2 (median [95% CI]) | 1.70 (1.05 to 2.70) | 0.47 (0.28 to 1.00) | <0.00100 |
| Osteoblastic surfaces (%; median [95% CI]) | 13.00 (10.20 to 15.20) | 3.40 (1.20 to 7.30) | <0.00100 |
| Double tetracycline–labeled surfaces (%; median [95% CI]) | 15.00 (9.00 to 18.50) | 1.30 (0.00 to 3.20) | <0.00100 |
| Al-stained surfaces (%; median [95% CI]) | 0.00 (0.00 to 7.50) | 28.50 (17.00 to 50.30) | <0.01000 |
| Post-PTX hypoparathyroidism (yes/no) (n) | 0/18 | 8/40 | <0.01000 |