Figure 9.

Effect of brivaracetam (BRV in (a)) and levetiracetam (LEV in (b)) on the development of corneal kindling in mice. Values given are the percentage of animals with secondarily generalized seizures; brivaracetam and levetiracetam were administered 30 and 60 min, respectively, before each of the twice-daily stimulations. The hatched line indicates a 2-day wash-out period without stimulation. After that period, the animals were restimulated twice daily for an additional period of 5 days without drug treatment.