Figure 4.

Effects of the CB₁ receptor agonist ACEA (50 μg) and the CB₂ receptor agonist JWH-015 (50 μg) on expression of proteins secreted by mast cells. In (A) rMCP-5 and (B) NGF protein expression is shown by a representative western blot (a) and relative densitometric analysis (b). Tubulin expression is shown as a control. Data are expressed as mean±s.e.mean of three separate experiments. ^*P<0.05, ^**P<0.01, ^***P<0.001 vs saline; ^□□P<0.01, ^□□□P<0.001 vs λ-carrageenin (CAR) alone.