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. 2008 Sep;57(9):2402–2412. doi: 10.2337/db08-0244

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Copyright © 2008, American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 5. — Functionality of islet grafts in diabetic recipients. A: Blood glucose levels in Id1^+/−Id3^−/− and wild-type Id1^+/+Id3^+/+ mice after streptozotocin injection. Shadowed area marks the limit of blood glucose values above which mice were considered frankly diabetic. B–D: Levels of blood glucose in mice rendered diabetic by streptozotocin and 1 week later transplanted with 500 (B), 200 (C), or 75 (D) wild-type islets per mouse. Values are means ± SE of measurements from the indicated number of mice.