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. 2008 Sep;57(9):2445–2452. doi: 10.2337/db07-1820

FIG. 6.

FIG. 6.

A1C (A) and GG (B) rise as the 14C-3OMG Ci-to-Co ratio increases. The GG is a measure of variance in A1C relative to glycated serum proteins. Across the population, intracellular sugar rises relative to extracellular, as does hemoglobin glycation relative to the glycation of extracellular proteins. Values of r2 are shown to demonstrate the fraction of the variance in A1C and GG accounted for by Ci-to-Co ratio. In contrast (Table 2), fructosamine has no significant slope relative to Ci-to-Co ratio.