TABLE 4.

Summary of linkage results reported on chromosome 3q

Authors	Study design	Phenotype	MLS	Markers	Genetic position*
Studies in type 1 diabetes
Moczulski et al. (8) (Caucasians)	DSP (n = 66)	Proteinuria and ESRD	3.1	D3S1308	157.0
Osterholm et al. (20) (Caucasians)	DSP (n = 83)	Proteinuria	2.7	D3S3606–D3S3694	134.6–148.8
Current study (Caucasians)	DSP (n = 50) DSP (n = 50)	Proteinuria ESRD	1.5 1.1	rs1002200 rs1381768	95.6 154.2
Studies in type 2 diabetes
Imperatore et al. (24) (Pima Indians)	ASP (n = 90)	Proteinuria and ESRD	1.5	D3S3053	174
Bowden et al. (25) (African Americans)	ASP (n = 206)	ESRD	1.3 (4.6)†	D3S2460	126
Krolewski et al. (21) Caucasians)	Quantitative trait loci using 5,656 relative pairs	UAE	1.0	D3S1744	153.4
Placha et al. (22) (Caucasians)	Quantitative trait loci using 5,187 relative pairs	GFR estimated by cystatin C (nondiabetic relative pairs only)	2.8	D3S1744	153.4
Chen et al. (26) (West Africans)	Quantitative trait loci using 360 relative pairs	Serum creatinine	2.2	D3S2418	210

^*cM according to the deCODE map.

^†Ordered subset analysis.