Skip to main content
. 2008 Aug 6;3(8):e2847. doi: 10.1371/journal.pone.0002847

Figure 7. Differential expression of growth factors and cytokines in AA astrocytes.

Figure 7

A. Confirmation of two differentially expressed growth factor genes by qRT-PCR in human normal ONH astrocytes: insulin-like growth factor binding protein 5 (IGFBP5) and heparin-binding EGF-like growth factor (HBEGF). Genes were normalized to 18S. Graphical representation of the relative mRNA levels in normal AA and CA astrocytes (n = 8, respectively, two-tailed t-test was used. * indicate p<0.05). B, C. Seven CA samples and six AA samples were used in ELISA experiment. B. The total amount of secreted and intracellular HBEGF is significantly lower in AA astrocytes compared to CA astrocytes (** indicated p<0.01 in two-tailed t-test) C. The level of secreted IL-6 is significantly lower in AA astrocytes compared to CA astrocytes (* indicated p<0.05 in two-tailed t-test).