Table 2.
List of nsSNPs that were predicted to be of functional significance by PupaSuite
| SNPs ID | Alleles | Region | Functional significance |
|---|---|---|---|
| rs1800072 | A/G | Coding nonsynonymous | Cellular processing |
| rs35516286 | C/T | Coding nonsynonymous | Cellular processing |
| rs1800080 | A/G | Coding nonsynonymous | Cellular processing |
| rs34911792 | G/T | Coding nonsynonymous | Cellular processing |
| rs1800092 | A/C/G | Coding nonsynonymous | Prot.structure and dynamics |
| Functional Sites | |||
| rs1800093 | G/T | Coding nonsynonymous | Prot.structure and dynamics |
| rs35813506 | A/G | Coding nonsynonymous | Prot.structure and dynamics |
| rs1801178 | C/T | Coding nonsynonymous | Prot.structure and dynamics |
| rs11531593 | A/C | Coding nonsynonymous | Prot.structure and dynamics |
| rs1800112 | C/T | Coding nonsynonymous | Functional Sites |
| rs766874 | A/G | Coding nonsynonymous | Cellular processing |
| Functional Sites | |||
| Exonic splicing enhancers | |||
| rs1800073 | C/T | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800074 | A/T | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800078 | C/T | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800079 | A/G | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800086 | C/G | Coding nonsynonymous | Exonic splicing enhancers |
| rs35032490 | A/G | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800097 | A/G | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800100 | C/T | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800103 | A/G | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800107 | G/T | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800110 | C/T | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800120 | G/T | Coding nonsynonymous | Exonic splicing enhancers |
| rs1800123 | C/T | Coding nonsynonymous | Exonic splicing enhancers |
| rs11971167 | A/G | Coding nonsynonymous | Exonic splicing enhancers |
| rs4148725 | C/T | Coding nonsynonymous | Exonic splicing enhancers |
| s1800501 | C/G | mRNA | Exonic splicing enhancers |
| rs1042166 | A/T | mRNA | Exonic splicing enhancers |
| rs1800501 | C/G | mRNA | Exonic splicing enhancers |
| rs1800080 | A/G | Coding nonsynonymous | Cellular processing |
| Exonic splicing silencers | |||
| rs1800099 | A/G | Coding nonsynonymous | Exonic splicing silencers |
| rs1800101 | C/T | Coding nonsynonymous | Exonic splicing silencers |