Figure 4.

(A) Sequence comparison of RecD family enzymes in the region of the pin domain (blocked in yellow). Enzyme sequences are E. coli, Salmonella typhimurium (S. typhi), Pseudomonas aeruginosa (P. aeru), Vibrio cholerae (V. chol), D. radiodurans (D. radio) and Haemophilus influenzae (H. infl). (B) Structure of the pin in D. radiodurans RecD2, shown in yellow. (C) Difference electron density map showing the location of the iodine atoms (tan) and the pin domain (grey). The protein and DNA are coloured using the same scheme as Figure 2. Domain 1A is coloured green and domain 1B (pin) is in yellow.