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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Chem Biol Drug Des. 2008 Jun 11;72(1):27–33. doi: 10.1111/j.1747-0285.2008.00676.x

Figure 2.

Figure 2

The effect of adding Leu to the N-terminus of PRG sequence and size reduction of the cyclic peptide on the biological activity of cIBR derivatives. Adding Leu residue to the N-terminus of PRG sequence in cIBR-4 enhances the activity of the peptide compared to cIBR-1. Size reduction of the cIBR-1 peptide to cIBR-7 maintains the activity of the peptide.