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Effects of 90% K+ channel inhibition and 100% increase in IP3 production at t = 100 s on microdomain (A) and cytosolic (B) Ca2+ currents, with the common-store model. The scale in B has been reduced for clarity; the cytosolic SERCA and voltage-operated Ca2+ (VOCa) currents peak at +73 and −103 pA, respectively.
