Fig. 1.
Effect of baclofen on the firing activity of labeled paraventricular nucleus (PVN) neurons in Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR). A and B, top: frequency histograms showing the effect of 10 μM baclofen on the firing activity of labeled PVN neurons in WKY rats (A) and SHR (B); bottom: representative tracings showing the spontaneous firing activity of the same neurons during control, application of baclofen, and washout. C: summary data showing the effects of baclofen (10 μM) on the firing activity of labeled PVN neurons in WKY rats and SHR. D: summary data showing the percent inhibition of the firing activity of labeled PVN neurons in WKY rats and SHR. Data are means ± SE. *P < 0.05 compared with control in C and with WKY rats in D. Bac, baclofen.